Lab Technician (Assay Development) – Preclinical and Analytical Development

Assay Development


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Siehe Firmendetails

Kontakt: Gwen Kerforn
Telefon: +43 1 890 63 60

About HOOKIPA:

HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA’s platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA’s pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.  

Position Summary:

We are looking for a highly motivated Lab Technician with a strong background in assay development (cell-based assays, fluorescent staining techniques and qPCR) and virology to join our team. Focus of the Assay Development unit is to establish and perform assays for product characterization. With a strong emphasis on assay development, this position aims to contribute to broaden the Hookipa assay portfolio. This position is primarily laboratory based.

 

Main Responsibilities:

  • Development and optimization of analytical assays for product characterization
  • Plan, execute and analyze novel cell-based assays and/or qRT-PCR methods (under BSL-2 conditions) acc. to timelines
  • Data analysis and evaluation, monitoring of assay performance (trending), troubleshooting by integrating a broad biological, as well as technical understanding
  • Preparation, review and revision of relevant documentation for all work processes according to Quality standards (e.g. technical reports, assay qualification reports, …)
  • Serve as SME in assay transfers – lead assay transfers
  • Maintenance of laboratory equipment and stock keeping

 

Qualifications & Skills:

  • MTA, BTA, Dipl. Ing. (FH) or B.Sc., M.Sc. in relevant field (e.g. Biology, Microbiology, Biotechnology, Immunology) or related subject in life science
  • At least 2 years years hands-on laboratory experience in the field of virology or immunology
  • Experience with immunological, virological or molecular biological techniques (e.g. cell-based assays, FACS analysis, WB, ELISA, qPCR)
  • Strong background in assay development is of advantage
  • Independent, well-organized and proactive work style
  • Creative and communicative team player with a strong sense of analytical and strategic thinking who is able to work both, independently and as part of an (interdisciplinary) team
  • Substantial knowledge and experience with Quality systems (e.g. GMP; GLP)
  • Experience working in biopharmaceutical or biotechnology industry is of advantage
  • Fluent in English, both spoken and written
  • Valid EU working permit

What we offer:

  • Strong team with dedicated and passionate employees
  • State of the art infrastructure
  • An excellent working atmosphere
  • Opportunities for personal development
  • Employee benefits such as health screening, public transportation card, Sodexo pass
  • Working in a multinational and multicultural environment

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary for this position is EUR 2.754,- based on fulltime (40 hours per week); depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible

Contact:

If you (m/f/d) are interested in this challenging position, please send your CV including a cover letter (summarizing your qualification and experiences) as well as your credentials to: talent@hookipapharma.com

For more information on HOOKIPA please visit www.hookipapharma.com

 


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