Post Doc position

Genome engineering in the yeast Pichia pastoris

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Kontakt: Jasmin Weber
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Post Doc position

Genome engineering in the yeast Pichia pastoris

in Vienna / Austria for 40 hours a week


That’s the project

The yeast Pichia pastoris is an important host for the production of industrial enzymes and biopharma-ceutical proteins. Typically, the expression cassettes are integrated into the genome by homologous recombination into a predefined locus. Multicopy strains containing multiple copies of the expression cassettes are usually associated with higher productivity but have been shown to be instable sometimes.

To accelerate strain development, highly efficient methods for gene integration are needed. In this project, we aim to establish novel methods for gene integration in P. pastoris based on DNA modifying enzymes. This also includes the development and evaluation of novel means of transformation. The resulting strains will be characterized for growth and productivity in high throughput screening and bioreactor cultivations. Genome integration events will be analyzed by genome sequencing.


That could be your future me

You are working in an enjoyable work climate, have numerous possibilities for further education and personal development. You are part of a challenging and helpful work environment full of team spirit and enthusiasm for your job. You expand your expertise and bridge your science to industry.

And not to forget: You make your research visible and broaden your network!


That’s important to us

In the best way you have completed a completed Master and PhD degree (or equivalent) in molecular biology, genetics, biotechnology, biochemistry, or similar study. Research experiences in the following areas would be fine:

  • Strong background in synthetic biology, genome engineering, molecular biology, biotechnology, or related disciplines
  • Practical experience in synthetic biology and/or molecular biology requested, and scientific interest in yeast cell biology and bioreactor cultivation desired.
  • Excellent skills in spoken and written English, an organized approach with strong attention to detail and good communication skills with ability to work well in teams.


That’s what you should know

Research will take place in the Institute of Microbiology & Microbial Biotechnology at the Department of Biotechnology of the University of Natural Resources and Life Sciences Vienna (BOKU)

  • minimum yearly gross payment of EUR 44,000 (Post Doc 40 h/week).
  • Start: beginning with July 2021 - duration for 2 years


Scientific Contact:

Assoc. Prof. Brigitte Gasser –

Prof. Diethard Mattanovich –


And now it’s your turn! Give us an idea of who you are.


Apply here:  I 06_2021

Application deadline: 10th of June 2021

Of course, we welcome applicants of all sexes (m/w/x), backgrounds and ages.

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