(Senior) Lab Technician – Preclinical Development

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Siehe Firmendetails

Kontakt: Gwen Kerforn
Telefon: +43 1 890 63 60

About Hookipa:

HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA’s platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA’s pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.

Position Summary:

We seek an experienced, highly motivated (Senior) Lab Technician to join our team in a fast-paced drug discovery environment. In the Preclinical Development team, you will focus, together with scientists and peers, on developing novel therapies, characterizing the immunogenicity and efficacy of candidate therapies in a range of preclinical models and contribute to moving lead candidates into clinical development. This position covers both in vivo and in vitro techniques involving work in the laboratory and animal facility.

Main Responsibilities:

  • Perform a variety of immunological assays including multicolor flow cytometry, ELISA, ELISpot, and multiplex cytokine profiling
  • Primary cell and cell line culture
  • Work with infectious materials under BSL-2 conditions
  • In vivo oncology pharmacology studies including mouse handling, surgeries, compound administration and preparation of tissue samples for ex vivo analysis
  • In vivo assessment of the therapeutic effect of candidates (monitor tumor growth)
  • Prepare documentation in accordance with Hookipa guidelines
  • Support preparation of lab procedures, protocols, reports, and SOPs
  • Address and solve simple problems within own assigned area of responsibility
  • Work under supervision and independently
  • Independently search for information in scientific and technical literature
  • Ability to work on weekends and statutory holidays


  • MTA, BTA or  B.Sc. or M.Sc. or equivalent in relevant field (e.g., Biology, Immunology, Microbiology, Biotechnology)
  • Detailed knowledge of multi-parameter flow cytometry and proficiency in FACS data analysis (FlowJo)
  • Experience with cell culture and immunological assays
  • Strong MS Office and data analysis software skills (GraphPad Prism, FlowJo)
  • Solid knowledge of animal welfare regulations
  • Basic knowledge in mouse handling, anatomy, blood, and tissue collection
  • Knowledge in anesthesia, surgery, in vivo imaging, and dosing techniques are a plus
  • Independent, efficient, and proactive
  • Motivated, flexible team player with the ability to handle multiple tasks in parallel and deliver high quality results under tight timelines
  • Strong interest in working in a creative environment and participate in all aspects of preclinical development
  • Eager to learn and develop new techniques
  • Excellent communication skills in English, German is a plus

What we offer:

  • Strong international team with dedicated and passionate scientists and technicians
  • State of the art infrastructure
  • Opportunities for personal development
  • Employee benefits such as health screening, public transportation card, Sodexo pass
  • Working in a multinational and multicultural environment

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary for this position is 2.754,- based on fulltime (40 hours per week); depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible


If you are interested in this challenging position, please send your CV including a cover letter summarizing your qualification and experiences to: talent@hookipapharma.com

For more information on HOOKIPA please visit www.hookipapharma.com



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