About Hookipa:

HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA’s platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA’s pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.

Position Summary:

HOOKIPA’s Preclinical Development Team is seeking an experienced, highly motivated Animal Technician to join our team in a fast-paced drug development environment. In the Preclinical Development Team, you will, together with scientists and peers, test novel immuno-oncology therapies in vivo. You will perform experiments to evaluate immunogenicity and efficacy of candidate therapies in a range of preclinical mouse models for human disease, thereby contributing to the identification and characterization of lead candidates and moving them into clinical development.

Main Responsibilities:

• Perform in vivo oncology pharmacology studies in mice in accordance with HOOKIPA licenses and Austrian legislation with regards to the use of animals in scientific research
• Handling and restraint of laboratory mice
• Perform identification procedures
• Cell and therapy administration
• Induction and maintenance of anesthesia
• Assist with and perform surgery for orthotopic mouse tumor models
• Provide post-operative monitoring and recovery care, including pain and distress assessment and administration of analgesics and other medication, as prescribed
• Weighing of animals
• Assessment of the therapeutic effect of candidates
• Observe, monitor, and report health status of laboratory mice
• Collect biological specimens for ex vivo analysis
• Perform euthanasia and necropsy of mice according to established standards
• Experience with in vivo imaging technology is a plus
• Work with infectious material under BSL-2 conditions
• Maintain documentation, charts, and records in accordance with HOOKIPA guidelines
• Work under supervision and independently
• Ability to work on weekends and statutory holidays

Required Qualifications:

• Trained animal caretaker (Tierpfleger) or B.Sc./M.Sc. or equivalent in relevant field (e.g., Biology, Immunology, Microbiology, Biotechnology)
• MS Office skills
• Data analysis software skills are a plus (GraphPad Prism)
• Solid knowledge of animal welfare regulations
• Good skills in mouse handling, anatomy, anesthesia, blood and tissue collection, basic surgery, and a good level of proficiency in various dosing techniques
• Independent, efficient, and proactive
• Motivated, flexible team player with the ability to handle multiple tasks in parallel and deliver high quality results under tight timelines
• Strong interest in working in a creative environment and participate in all aspects of preclinical development
• Eager to learn and develop new techniques
• Excellent communication skills in English, German is a plus

What we offer:

• Strong international team with dedicated and passionate scientists and technicians
• State of the art infrastructure
• Opportunities for personal development
• Employee benefits such as health screening, public transportation card, Sodexo pass
• Working in a multinational and multicultural environment

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary for this position is 2.754,- based on fulltime (40 hours per week); depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible

Contact:

If you are interested in this challenging position, please send your CV including a cover letter summarizing your qualification and experiences to: talent@hookipapharma.com

For more information on HOOKIPA please visit www.hookipapharma.com.