(Senior) Animal Technician – Preclinical Development


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Siehe Firmendetails

Kontakt: Gwen Kerforn
Telefon: +43 1 890 63 60

About Hookipa:

HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA’s platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA’s pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.

Position Summary:

HOOKIPA’s Preclinical Development Team is seeking an experienced, highly motivated Animal Technician to join our team in a fast-paced drug development environment. In the Preclinical Development Team, you will, together with scientists and peers, test novel immuno-oncology therapies in vivo. You will perform experiments to evaluate immunogenicity and efficacy of candidate therapies in a range of preclinical mouse models for human disease, thereby contributing to the identification and characterization of lead candidates and moving them into clinical development.

Main Responsibilities:

  • Perform in vivo oncology pharmacology studies in mice in accordance with HOOKIPA licenses and Austrian legislation with regards to the use of animals in scientific research
  • Handling and restraint of laboratory mice
  • Perform identification procedures
  • Cell and therapy administration
  • Induction and maintenance of anesthesia
  • Assist with and perform surgery for orthotopic mouse tumor models
  • Provide post-operative monitoring and recovery care, including pain and distress assessment and administration of analgesics and other medication, as prescribed
  • Weighing of animals
  • Assessment of the therapeutic effect of candidates
  • Observe, monitor, and report health status of laboratory mice
  • Collect biological specimens for ex vivo analysis
  • Perform euthanasia and necropsy of mice according to established standards
  • Experience with in vivo imaging technology is a plus
  • Work with infectious material under BSL-2 conditions
  • Maintain documentation, charts, and records in accordance with HOOKIPA guidelines
  • Work under supervision and independently
  • Ability to work on weekends and statutory holidays

Required Qualifications:

  • Trained animal caretaker (Tierpfleger) or B.Sc./M.Sc. or equivalent in relevant field (e.g., Biology, Immunology, Microbiology, Biotechnology)
  • MS Office skills
  • Data analysis software skills are a plus (GraphPad Prism)
  • Solid knowledge of animal welfare regulations
  • Good skills in mouse handling, anatomy, anesthesia, blood and tissue collection, basic surgery, and a good level of proficiency in various dosing techniques
  • Independent, efficient, and proactive
  • Motivated, flexible team player with the ability to handle multiple tasks in parallel and deliver high quality results under tight timelines
  • Strong interest in working in a creative environment and participate in all aspects of preclinical development
  • Eager to learn and develop new techniques
  • Excellent communication skills in English, German is a plus

What we offer:

  • Strong international team with dedicated and passionate scientists and technicians
  • State of the art infrastructure
  • Opportunities for personal development
  • Employee benefits such as health screening, public transportation card, Sodexo pass
  • Working in a multinational and multicultural environment

 

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary for this position is 2.754,- based on fulltime (40 hours per week); depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible

Contact:

If you are interested in this challenging position, please send your CV including a cover letter summarizing your qualification and experiences to: talent@hookipapharma.com

 

For more information on HOOKIPA please visit www.hookipapharma.com.

 


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